Functional relationships between cricopharyngeal sphincter and oesophageal body in response to graded intraluminal distension.
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چکیده
منابع مشابه
Functional relationships between cricopharyngeal sphincter and oesophageal body in response to graded intraluminal distension.
Responses of the cricopharyngeal sphincter to graded intraluminal distension were studied in order to determine its response threshold and to define the functional relationship between the sphincter and oesophageal body. Nine normal subjects underwent manometric study using a multilumen tube with an attached inflatable balloon sited 10 cm below the sphincter. Sphincteric and oesophageal motor r...
متن کاملFailure of transient lower oesophageal sphincter relaxation in response to gastric distension in patients with achalasia: evidence for neural mediation of transient lower oesophageal sphincter relaxations.
Transient lower oesophageal sphincter relaxation (LOSR) is the major mechanism underlying gastro-oesophageal reflux. The mediation and control of LOSRs are incompletely understood but evidence suggests a neural inhibitory mechanism. In this study we have evaluated the effect of gastric distension on LOS function in 16 patients with untreated idiopathic achalasia and compared it with that in 10 ...
متن کاملFailure of transient lower oesophageal sphincter relaxation in response to gastric distension in patients with achalasia: evidence for neural mediation of transient lower oesophageal sphincter relaxations
Transient lower oesophageal sphincter relaxation (LOSR) is the major mechanism underlying gastro-oesophageal reflux. The mediation and control of LOSRs are incompletely understood but evidence suggests a neural inhibitory mechanism. In this study we have evaluated the effect of gastric distension on LOS function in 16 patients with untreated idiopathic achalasia and compared it with that in 10 ...
متن کاملCholecystokinin in transient lower oesophageal sphincter relaxation due to gastric distension in humans.
BACKGROUND AND AIMS Transient lower oesophageal sphincter relaxations (TLOSRs) has been found to be the main mechanism of gastro-oesophageal reflux. In dogs, cholecystokinin (CCK) is involved in their occurrence. The aim was to evaluate the role of endogenous and exogenous CCK in the occurrence of TLOSRs induced by gastric distension at constant pressure in humans. METHODS Ten healthy volunte...
متن کاملRelaxation of the Cricopharyngeal Sphincter by Suxamethonium.
The pattern of relaxation of the cricopharyngeal sphincter by suxamethonium was studied in fifty patients. The pattern was variable, but a large percentage of the cases showed an abrupt initial fall in cricopharyngeal sphincteric tone concomitant with, or just preceding, the onset of fasciculations, although relaxation often only reached completion after fasciculations had ceased. Of twenty-thr...
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ژورنال
عنوان ژورنال: Gut
سال: 1988
ISSN: 0017-5749
DOI: 10.1136/gut.29.2.161